Frequency of reduced vancomycin susceptibility and heterogeneous subpopulation in persistent or recurrent methicillin-resistant Staphylococcus aureus bacteremia.

نویسندگان

  • Amir Khosrovaneh
  • Kathleen Riederer
  • Sajjad Saeed
  • M Shamse Tabriz
  • Amar R Shah
  • Michel M Hanna
  • Mamta Sharma
  • Leonard B Johnson
  • Mohammad G Fakih
  • Riad Khatib
چکیده

Vancomycin susceptibility was checked in isolates from initial and final blood samples obtained from 22 patients with persistent or recurrent methicillin-resistant Staphylococcus aureus bacteremia. The minimum inhibitory concentration of vancomycin was determined using Etest and found to have increased in 2 pairs of isolates, and results of screening in 4 mu g vancomycin and a modified population analysis profile suggested heteroresistance in 3 isolates (13.6%). Heteroresistance is not a common cause of persistent or recurrent bacteremia.

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 38 9  شماره 

صفحات  -

تاریخ انتشار 2004